Advanced methods or preservation of biological activity

Design

Analysis

Biotesting

of

 Strong Spirits - from the 16th century painting

Natural Products



CONSULTING AND CONTRACT RESEARCH SERVICES

Design Development Analysis
Formulation Stability and bioavailability studies Identification and quantification of chemical markers and bioactive ingredients
Development of structural and functional claims Method/process development and optimization Assay/test development


We provide solutions in the area of identification and quantification of biological effects

through the combination of expertise in test design/applications and experience in natural product development

BIOTESTING
In vitro, ex vivo, in vivo and cell culture assays employed to characterize the effect of compound on activity of body systems and organs, cellular, physiological, pharmacological response and effects on pathological conditions.



Currently available bioassays include but are not limited to:
Evaluation of effect on immune response, endocrine response, behavioral response, enzyme activity assays, receptor binding assays, cytochrome induction, neurotransmitter release, antioxidant effects, cell proliferation assays, blood coagulation tests, gastric functions tests. Examples:

Antioxidant activity

Antibacterial activity

Antifungal activity

Anti-inflammatory action

Antiulcer, gastroprotective activity

Stimulation of immune response

Bronchidilatatory, mucolytic, antihistamine and antiastmatic action

Biochemical, neurochemical and endocrine assays

Cardiotropic effects

Cerebrovascular effects

Effects on brain activity, CNS functions, memory and behavior

Potentiation of antiviral activity


We can offer flexible research protocols adjusted to particular product situation

Examples:
"Quick and dirty" - verifies if certain bioassay is suitable for the analysis of biological activity of the sample

"Assay screening" - Search for bioassay(s) appropriate for the evaluation of the activity of the product

"Reproducible effect" - provides statistically significant data on the activity of the sample in selected bioassay(s)

"Extensive study" - investigation of the biological effects of the sample organized and developed to the level of scientific publication

 

Projects, proposals and obtained results are treated in full confidentiality

Tests are conducted according to a blind protocol and are confirmed in independent laboratories

Call or e-mail to arrange for a free 15 minutes discussion of the project
Floraleads Group, PO Box 5546, CARY, NC 27512
919-303-1420 please send inquiries to this address

natural health products developed by Floraleads GR